This episode we look at cannabis and it’s effect on sleep and body temperature, a story on what’s after terpenes in the quest for flavour, data deals can cost a lot in fines, a look at the cannabinoid THCV and we stop on Cultivar Corner, brought to you by Up in Smoke, we’re back in the Salmo area for Kootenay Cultivar’s upcoming OJ Zainbow!
This episode we look at cannabis and it’s effect on sleep and body temperature, a story on what’s after terpenes in the quest for flavour, data deals can cost a lot in fines, a look at the cannabinoid THCV and we stop on Cultivar Corner, brought to you by Up in Smoke, we’re back in the Salmo area for Kootenay Cultivar’s upcoming OJ Zainbow!
Kootenay Cultivar at Up in Smoke
00;00;01;22 - 00;00;08;29
Ian
From a studio high above the clouds of the Okanagan Valley. This is the cannabis potcast.
00;00;09;01 - 00;00;19;08
Ian
Exploring the world of Canadian cannabis culture. One toke at a time. Here is your host and budtender, Gary Johnson.
00;00;19;10 - 00;00;44;15
Gary Johnston
And that is my opportunity to welcome you back to the Cannabis Potcast. Thank you for coming back one more time. I so appreciate that. Or perhaps I'm wrong. This may be your very first time here. If it is, well, let me offer you an especially warm welcome. And before we get too much further, I want to remind you that this podcast is intended for those of legal consumption age in your jurisdiction and is intended purely for entertainment and perhaps educational purposes.
00;00;44;17 - 00;01;12;21
Gary Johnston
You should always consume your cannabis responsibly. In episode 183 of the Cannabis Potcast, we're going to look at cannabis and sleep and cannabis and your body temperature because apparently it can have an effect on both. Another of our cannabinoids comes to the fore. This one is THC v, which we'll dive into a little bit and discussion on what comes after terpines, because we always talk about terpines that have some of the components of flavor, but there's more components that really are involved in the flavor of cannabis.
00;01;12;21 - 00;01;36;25
Gary Johnston
We'll dive into that. And that's also going to come up on Cultivar Corner because Thilo's is one of those components. And that's going to be featured in today's Cultivar Corner, brought to you by Up in Smoke where we're going to Kootenay Cultivar. And we're trying their upcoming OJ Zane Bow, all of that and more on episode 183 of the Cannabis Potcast.
00;01;36;27 - 00;01;53;03
Gary Johnston
And of course, before we get too much further, let me thank you for being a listener. I truly appreciate the fact that you are here each and every time, and I want to thank my supporters as well. Georgina at buy Me a coffee.com/Cannabis Potcast. If you feel so inclined and you like what you hear, you can go there too and buy me a doobie.
00;01;53;06 - 00;02;17;13
Gary Johnston
And I want to thank my patrons on Patreon. Thanks to Tony, Rob, Gage, Lloyd, and Roger. I appreciate your support each and every time. And now let's get to our first story. And we're going to for 20 intercom, which may be surprising to some people, cannabis can help some people, but not everyone sleep. A study explains THC can help young adults with depression or anxiety, but otherwise could worsen sleep problems.
00;02;17;15 - 00;02;44;10
Gary Johnston
Many insomniacs swear by cannabis as a way to help them sleep. While many scientific studies have found the THC actually exacerbates sleep problems, a new study published last week in addiction might explain why. Researchers from the University of Southern California's Keck School of Medicine found that for young adults with preexisting depression or anxiety, cannabis improved sleep. For those without preexisting mental health conditions, it created more sleep problems.
00;02;44;12 - 00;03;18;03
Gary Johnston
There's a common perception that cannabis can improve sleep, but the science on cannabis effects on sleep is mixed. And part of the reason could be because individual factors like mental health play a role in how cannabis use affects sleep, says Claire Walsh, a PhD student in behavioral health at USC and lead author of the study. Walsh and her team used data from USC Happiness and Health Study, which surveyed 3300 public high school students in the Los Angeles area on their substance use, social and emotional health, as well as other health factors between 2013 and 2023.
00;03;18;06 - 00;03;46;23
Gary Johnston
The study compared people who use cannabis 20 or more days each month, with those who have never tried it, and determined how cannabis affects sleep problems using a 16 point scoring system. Walsh says that for participants who were anxious or depressed, her team saw an average decrease in sleep problems of -1.18 points over six months, and for participants without anxiety or depression, they saw an average increase in sleep problems of 1.66 points over six months, compared with those who didn't use cannabis.
00;03;46;25 - 00;04;08;24
Gary Johnston
Most isn't sure why cannabis affected people with anxiety or depression differently. One possibility is that THC helps mask the symptoms of anxiety or depression, which can have a negative impact on sleep. However, this doesn't necessarily mean cannabis is treating the underlying mental health conditions, she emphasized. Research shows that people who use cannabis are more likely to have anxiety and depression.
00;04;08;26 - 00;04;31;07
Gary Johnston
And evidence is mixed on whether or not the cannabis is helping. Sleep is regulated by the endocannabinoid system, and that cannabis tickles the endocannabinoid system, and that even though we don't know the exact pathway, we know that the endocannabinoid system mediates sleep, says Peter Grinspoon, a physician and Harvard Medical School instructor who wrote Seeing Through the Smoke about medical cannabis.
00;04;31;09 - 00;04;51;08
Gary Johnston
Grinspoon says that people with anxiety or depression might find cannabis more beneficial for sleep because they're more likely to struggle with insomnia in the first place. It's easier to help someone who has a problem than someone who doesn't, he said. Another possible explanation for the varying effects could be that people use cannabis differently if they're trying to sleep, rather than get high.
00;04;51;10 - 00;05;17;09
Gary Johnston
The USC study investigated how frequently people use cannabis containing THC, but not the size of their dose or their method of consumption. Grinspoon says that people who consume cannabis with the specific intention of improving their sleep quality likely use lower doses because high doses can be stimulating and keep people awake. Grinspoon suspects that much of the scientific research showing cannabis hurts sleep quality is using skewed methodologies.
00;05;17;11 - 00;05;37;19
Gary Johnston
A lot of the cannabis research has been done under the auspices of the War on Drugs, and there's been a huge, major emphasis on finding harms and very little emphasis on finding benefits, he said. Restrictions on cannabis research also prevented researchers from studying cannabis in a lab setting, which means they must rely on real world data about whether cannabis participants happen to be using.
00;05;37;22 - 00;06;03;19
Gary Johnston
We've been studying illegal cannabis. God knows what's in it. That's like studying moonshine to try to understand alcohol. And then we've been studying smoked cannabis, which is the least healthy way to take it. Grinspoon added. Much of the more recent, specifically targeted research on cannabis in sleep shows promise. For example, a study from earlier this year looked at patients in the UK who treated their post-traumatic stress disorder, PTSD, with vaporized cannabis of the Hindu Kush strain.
00;06;03;21 - 00;06;30;14
Gary Johnston
The researchers chose Hindu Kush because it's a well-established cannabis strain with a stable genetic background and a well-characterized chemical and pharmacological profile. The study found the participants experienced significant sleep improvements over a period of six months. Even when cannabis does help people sleep, it still comes with risks. Like other sleep medications, cannabis carries a risk of dependance, and people who decide to quit might experience withdrawal symptoms, including even worse, insomnia.
00;06;30;16 - 00;06;54;19
Gary Johnston
Researchers have also raised concern over the fact that cannabis can reduce the amount of time people spend in rapid eye movement sleep, which means they'll have your dreams. Hypothetically, that could be a problem, said Grinspoon, adding that they still don't understand sleep well enough to know the implications of missed REM sleep. But he says other popular sleep aid medications also reduce REM sleep, so it's kind of a double standard for cannabis, as usual.
00;06;54;22 - 00;07;18;12
Gary Johnston
The interesting items in there about sleep from cannabis. Do you use it? Does it help you sleep? I know it certainly helps me sleep. And perhaps based on some of the content of that article, it shouldn't because I do tend to smoke the higher THC stuff late at night. But luckily for me it works. I guess we'll have to see if that carries on in the future.
00;07;18;15 - 00;07;49;20
Gary Johnston
And we're going to try and test income for the next story, which is Flavors and aromas in cannabis. What's after terpines? This was written by Chris Campana. Consumers are increasingly catching on to the role of chirping and in determining the various flavors, aromas and effects of cannabis. While emphasis was once placed on cannabinoid lights and who could breathe the highest tetrahydrocannabinol, THC cultivars trappings of taking center stage as the compounds in cannabis that make various cultivars unique, allowing the consumer to better target their desired cannabis experience.
00;07;49;23 - 00;08;14;25
Gary Johnston
What comes after terpenes when distinguishing the flavor, aroma, and effects of cannabis? What are the functions of the other compounds within cannabis, and how can they affect the cannabis experience? We're going to do a deep dive to examine what's after terpenes break down other plant components, including esters, thistles, aldehydes, and flavonoids. We'll also touch on efforts that use these various components to create new classifications for cannabis.
00;08;14;26 - 00;08;37;28
Gary Johnston
Beyond the indica and sativa binary esters and their effects on terpenes, while term beans are essential to the flavor and aroma expression of a cannabis cultivar. They don't get all the glory. Esters are also becoming increasingly important for cannabis geneticists trying to nail down flavor and aroma. Some of the most popular commercial cannabis cultivars boost flavors have banana, strawberry, or pineapple.
00;08;38;00 - 00;09;02;01
Gary Johnston
The similarities in aroma between the fruits and cannabis can be uncanny at times. However, this isn't due to terpenes, but rather esters. Esters are volatile compounds, compounds that can easily vaporize, the can add to, or change the flavor and aroma profile of terpenes. When scent compounds enter our nose, they tend to bind to our olfactory receptors in different concentrations and combinations.
00;09;02;03 - 00;09;25;25
Gary Johnston
Engaging the brain in scent identification. To use an example, the cultivar Strawberry Banana will smell like these fruits due to their esters, not because the same chirping is in strawberries and bananas are in the cannabis cultivar. It's important to note that esters, unlike some terrapins like beta, carry off and do not act on the endocannabinoid receptors. However, they are believed to modulate and mitigate chirping effects.
00;09;25;27 - 00;09;49;21
Gary Johnston
Files. Why cannabis smells like skunk. Many people would classify the smell of cannabis as akin to that of a skunk spray. In 2021, scientists at Bayer Scientific revealed that the skunky smell of cannabis was due to the compound three methyl two butane one Thile aka 321 MTY. Previous to this, it was believed that these funkiness had to do with terpines.
00;09;49;23 - 00;10;13;17
Gary Johnston
321 MT is a sulfur containing Thile, and is also one of seven styles found within a skunk spray, which directly explains the Santa Association. It's believed that the human olfactory system has evolved to detect sulfur containing files, even when they don't exist in high concentrations. 321 MT is also believed to be in some beers that elicit a skunky experience on the palate.
00;10;13;20 - 00;10;37;07
Gary Johnston
Aldehydes. Yet another enhancer of scent. But more research has yet to be uncovered about the exact role of aldehydes in the cannabis plant. These aromatic compounds are created through the dehydration of alcohol. Examples of aldehydes include the vanilla scent from the molecule vanillin, or the scent of almonds from Bens aldehyde. It's believed that aldehydes may be influenced by chemically changing their makeup.
00;10;37;09 - 00;10;58;05
Gary Johnston
It should be noted that not all aldehydes smell pleasant, like vanilla or almonds. Aldehydes are also created when a perishable product becomes rancid, which is why aldehydes need to be balanced to maintain a pleasant scent. It's usually recommended that products like cannabis oils are kept cold or at room temperature to avoid degradation and the creation of more aldehydes.
00;10;58;07 - 00;11;21;10
Gary Johnston
A flavonoids and the color of cannabis flavonoids make up anywhere from 2 to 10% of the chemical composition of cannabis, but there is still so much above them yet to be discovered. Flavonoids dictate the color of plants like flowers, fruit and the different colors of cannabis buds. Flavonoids are also said to influence the aroma and flavor of plants, but more research needs to be done on exactly how this occurs.
00;11;21;13 - 00;11;48;08
Gary Johnston
The research that exists reveals the therapeutic benefits of flavonoids, with some being investigated for their anti-cancer, anti-inflammatory, antioxidant, and neuroprotective properties, to name a few. Because of their similarities in medicinal properties. Flavonoids and terpenes work together as part of the magic of the entourage effect in their synergistic relationship with cannabinoids and other components of the plant. There's been a significant surge in the understanding of the other components of cannabis.
00;11;48;13 - 00;12;15;06
Gary Johnston
As the cannabis industry becomes more sophisticated and realizes that there is a lot more to the plant than THC, increasingly, cannabis producers are labeling their products by dominant genes, and cannabis researchers are looking for ways to use the non cannabinoid compounds in cannabis to work towards a new classification system for cultivars. Doctor Ethan Rousseau and Mark Lewis, PhD, have proposed Turpin superclasses as a way to group terpenes into families by their effects.
00;12;15;08 - 00;12;49;07
Gary Johnston
Rousseau and Lewis propose their classification system begins with using limonene. Alpha pinyin and beta carry off offline. Philip Henry of VSL enterprises and the Flower Corporation has proposed a new classification system that hinges on the terpenes Mersenne limonene beta carry off the enter penalty, known as the Turpin superclasses. Henry was able to narrow down 18 SNPs, or single nucleotide polymorphisms, genetic variations from 1400 that could help classify cultivars into a Turpin family.
00;12;49;09 - 00;13;15;29
Gary Johnston
In the quest for a better classification system for cannabis connoisseurs, or looking beyond terpenes, and continuing to dig deeper to see what other compounds dictate effect, as well as a Roman flavor. With more being uncovered about the different components of cannabis. It becomes increasingly evident that it's more than just cannabinoids and terpenes that influence the cannabis experience. The good news is that the cannabis industry is embracing terpene as an indicator of effect, with a noted uptick in consumer interest.
00;13;16;01 - 00;13;39;22
Gary Johnston
As we dive deeper into understanding the compounds of cannabis beyond cannabinoids and beans, we can work towards a unified classification system for cannabis that will help consumers with their product choices. For now, there's still so much we don't know, but are beginning to unveil one cannabinoid Turpin ester, vial, aldehyde, and flavonoid at a time. What a great article and not a gain from Turpin and testing.
00;13;40;00 - 00;13;49;13
Gary Johnston
Com written by Chris Campagna. And now, you know, it's not just the terpines. It's the esters, the files, the aldehydes and all of that combined.
00;13;49;19 - 00;13;59;05
Ian
To achieve CBD tipping profiles. What's in me? Oh, please explain to me. Go to the core.
00;13;59;07 - 00;14;04;25
Unknown
Go. Go to the club. Oh, yeah. Go to the.
00;14;04;25 - 00;14;08;25
Ian
Portal. Please explain this stuff to me.
00;14;08;27 - 00;14;29;29
Gary Johnston
Welcome to Cultivar Corner. Brought to you by Up in Smoke at 258 West Broadway in Vancouver and online at It's Up in smoke.com. Check them out today for some direct delivery exclusives like we're sampling today from Kootenay Cultivar and their upcoming Ojai Rainbow. Now this is exclusive to the Direct delivery channel and lucky for you you'll see it soon.
00;14;29;29 - 00;14;54;00
Gary Johnston
It it's up in smoke.com. And if you're of legal age and live in B.C. when it arrives, you can check it out for yourself. Unfortunately, if you live in another part of Canada or another country, we'll just have to keep teasing you with it. And today we're heading back to the sawmill area of the kidneys. And this is from Kootenay Cultivar and we are trying their OJ Zane Zambo thc at 24%.
00;14;54;01 - 00;15;26;09
Gary Johnston
My dominant terps, beta Miocene limonene, Alpha pinyin, trans carry a lean and the dominant flavor compounds in the oj zambo are not terps, though it's files that are providing the flavor. And earlier in this episode you heard an article talking about the other components of cannabis flavor and aroma esters styles and, and and and others. So the files and let's talk about one particular file, which I think is what we're experiencing when we are trying this one.
00;15;26;12 - 00;15;45;07
Gary Johnston
So in the context of cannabis essential oils, files play a crucial role in determining the aroma and overall quality of the product. And the particular molecule we're talking about in this case is three methyl two butane, one file or three MT, which is responsible for the skunky aroma in cannabis.
00;15;45;10 - 00;15;46;02
Ian
00;15;46;02 - 00;16;13;24
Gary Johnston
And as I stick my nose into the jar and pull that out, there's definitely some skunk, there's some heavy diesel, there's some citrus, there's some pine. There is an abundance of aromas that is coming out of this jar. My goodness sakes. My first impression when I opened up the jar was loud. This is just really loud. There's so much coming up at that.
00;16;13;26 - 00;16;41;23
Gary Johnston
So before we get to try it, let's tell you a little bit about Courtney Cultivar and who they are. United by a diverse range of backgrounds, their team shares a common passion cannabis. Each member hails from the old guard with roots dating back to the 1990s, collectively bringing a wealth of experience and expertise into the cannabis space. It's this unique amalgamation of skills that sets us apart and allows us to craft extraordinary flowers for our clients.
00;16;41;25 - 00;17;01;22
Gary Johnston
With a shared love for the plant and a rich history in cultivation, our team, it couldn't be called FA, is dedicated to delivering an unparalleled cannabis experience and it starts at the top. Tyson Carmody, master grower and owner born into a vibrant hippie family in the heart of The Goonies, Tyson's roots in the craft cannabis culture run deep.
00;17;01;24 - 00;17;28;23
Gary Johnston
For over 25 years, he's been growing and perfecting his techniques, fueled by the unique perspective instilled in him by his family's ethos, Tyson eagerly attempted a myriad of courses and seminars, engaging with industry leaders in cannabis, natural farming, and soil sciences, and as a co-founder of Kootenay Cultivar, he brings his wealth of experience and expertise to the forefront, contributing to the company's reputation for producing some of the most esteemed cannabis in the nation.
00;17;28;25 - 00;17;59;07
Gary Johnston
Tyson's commitment to perfection echoed throughout his work, solidifying him as a distinguished authority in the industry and working with Tyson or Travis Hefner, the CEO and owner. Isaac Rogers, alternate master grower and owner. Sandra Ramsden, facility general manager and compliance team Jordan Austin, Chuck the lead grower, and Peter Reid, QA, a great team they have compiled and they're producing some pretty good cannabis.
00;17;59;09 - 00;18;20;26
Gary Johnston
And let's take a look at that. Cannabis. So this is OJ's rainbow, which is a cross of a rainbow and mints. And it is coming soon to the direct delivery channel. Let me pull it up and take a look at it under the jeweler's loop. Oh, so this is a very light green flower. That's its predominant color. Lot.
00;18;20;26 - 00;18;46;12
Gary Johnston
And lots of red hairs and lots and lots of trichomes that are distributed all around that beautiful flower. And again, the aromas just loud. Loud is the best way that I can describe that. Just just astounding. So how we know what it tastes like. We know what it smells like. We know that it is really nice looking flower, more great flower coming out of Selma.
00;18;46;12 - 00;19;15;08
Gary Johnston
And the goodness. It's astounding to me that that place has so much about it. And what they do. Just just amazing to me. So more on Kuti cultivar small batch legacy founded craft cannabis flourishes amidst the breathtaking landscape of the cooties. Located on an extraordinary 60 acre farm nestled in picturesque settlement BC. And it's time we tried some picturesque cannabis from salvo BBQ.
00;19;15;08 - 00;19;25;09
Gary Johnston
There. My mighty is ready. Let's take a taste of that.
00;19;25;11 - 00;19;46;13
Gary Johnston
Oh, and the abundance of flavors coming out of that farm. There's a hint of sky goodness. There's some diesel, there's some piney, there's some lime, there's some citrus. It is just an abundance of flavors in my mouth.
00;19;46;16 - 00;20;03;22
Gary Johnston
And smooth. Oh, nothing harsh coming out of the vaporizer. Oh, that's really nice. Really, really tasty. Let's fire up the joint. Let's try it from the other perspective and see what we get there. So this gain from Kootenay Cultivar.
00;20;03;25 - 00;20;04;09
Ian
Their.
00;20;04;12 - 00;20;32;08
Gary Johnston
Their rainbow 24% THC for. All very nice and smooth on enjoyed as well. My dominant terpenes myrcenes limonene alpha piney and trans caryophyilene. Now we talk about the thiols, but it hasn't been specifically identified what thiols are composed in. And maybe this is a new test and a new piece on the labels we're going to get soon.
00;20;32;11 - 00;20;38;06
Gary Johnston
Let's list the esters in the thiols along with the terpines.
00;20;38;09 - 00;20;49;25
Gary Johnston
Or as I pull that into my lungs, let my ex envelop those THC molecules and slap them into my CB1 receptors.
00;20;49;27 - 00;20;54;22
Ian
00;20;54;25 - 00;20;55;19
Ian
00;20;55;22 - 00;21;21;03
Gary Johnston
It's why I love doing Cultivar Corner first thing in the morning. It's my first taste of cannabis for the day, and it's really when I get to truly feel the effect of a new cannabis cultivar upon my ex, and the effect I'm feeling right now is feeling really good, really nice and chill. Oh, lots of euphoria happening right now.
00;21;21;03 - 00;21;35;08
Gary Johnston
Some nice body chill to oh, this is feeling really good. Let's get some more of the vaporizer.
00;21;35;11 - 00;21;36;12
Ian
Oh.
00;21;36;14 - 00;21;59;27
Gary Johnston
The amazing abundance of flavors that come out of them. Just astounding. And as I look at the ash on the joint. Nice gray ash development. I'm not seeing any hints of black in that. And when it's time to drop it off, it is time to drop it off. And here are the happy eyes.
00;22;00;02 - 00;22;03;12
Ian
Oh, oh,
00;22;03;14 - 00;22;37;09
Gary Johnston
I am loving this. It is astounding to me how the Samo area of the kidneys. Is producing so many amazing growers. Well, I guess it's the other way around. Is it? Samo has accumulated an amazing number of growers who are producing some pretty damn fine cannabis. And will it ever stop? I don't know, we'll keep on trying, but I sure am enjoying this.
00;22;37;11 - 00;22;51;12
Gary Johnston
This is a really nice euphoria. I'm feeling some nice body relaxation as well. This is just making me feel really chill. And I got to tell you, my room smells wonderful.
00;22;51;15 - 00;22;51;27
Ian
Both.
00;22;51;27 - 00;23;24;04
Gary Johnston
From the odor of the joint and coming out of the vaporizer. I'm loving the flavors. I'm loving the aromas. OJ's rainbow from Kootenay cultivar 24% THC beta Miocene limonene, alpha piney, trans carry off clean and some files for good measure. Remember, it's up in smoke.com. You can go there yourself once this is released and you can get you can try it for yourself if you're 19 years of age.
00;23;24;07 - 00;23;42;21
Gary Johnston
Unfortunately, again, if you're in another country or another province, we're just going to have to tease you with an, I'm not going to tease you any longer, though. This, this Kootenay cultivar, Ogi Rainbow, is responsible for for me.
00;23;42;23 - 00;23;45;22
Ian
Well.
00;23;45;24 - 00;24;20;24
Gary Johnston
I am I am so looking forward to my day. This is wonderful. And of course, after the things have rolled around my handle cannabinoid system for a while, it's just gotten deeper. Euphoria. Absolutely wonderful. The the energy and just the general chill feel. Just just I feel really, really nice. This is really nice, buzz. I'm just going to sit here and enjoy it for a while.
00;24;20;26 - 00;24;22;19
Ian
Sharing stories about good weed.
00;24;22;19 - 00;24;25;21
Gary Johnston
While trying good weed.
00;24;25;24 - 00;24;26;06
Ian
This is the.
00;24;26;06 - 00;24;52;15
Gary Johnston
Cannabis Potcast and realized we missed this last week last episode. So let's get back to it. Let's get back to our cannabinoid of the episode. And this from leafly.com. What is THC v and what are the benefits of this cannabinoid FCV or tetrahydrocannabinol. Therein is a compound in cannabis that offers a unique array of effects and medical benefits that sets it apart from other cannabinoids like THC and CBD.
00;24;52;17 - 00;25;21;13
Gary Johnston
Whether you're a medical marijuana patient looking for a particular type of relief or a casual consumer chasing a special effect, we'd like to introduce you to this fascinating compound that's sure to make major waves in the cannabis world as we discover and utilize its full potential. What are THC? These effects and benefits? Well, as its name suggests, THC is similar to THC in molecular structure and psychoactive properties, but it provides a variety of pronounced and altogether different effects.
00;25;21;15 - 00;25;47;15
Gary Johnston
A note for vapor enthusiasts THC has a boiling point of 420°F, or 220°C, so you'll need to turn it up higher than you would THC. THC is an appetite suppressant, in contrast to THC may delay the appetite. This may be good for consumers focused on weight loss, but THC should be avoided by patients treating appetite loss or anorexia.
00;25;47;17 - 00;26;20;06
Gary Johnston
THC may help with diabetes, research shows. Promise in THC vs ability to regulate blood sugar levels and reduce insulin resistance. THC may reduce panic attacks. It appears to curb anxiety attacks in PTSD patients without suppressing emotion may help with Alzheimer's. Tremors, motor control, and brain lesions associated with Alzheimer's disease appear to be improved by THC, but research is in progress, and THC stimulates bone broth because it promotes the growth of new bone cells.
00;26;20;06 - 00;26;48;05
Gary Johnston
THC is being looked at for osteoporosis and other bone related conditions. Where can I find THC v? If you're looking for the effects mentioned above, but you aren't sure where to start your search. Most strains only contain trace undetectable amounts of THC, making it difficult to achieve the desired therapeutic effects. Look for African sativa. Lab results show the THC is most abundant iniciativas, particularly Landry strains from Africa.
00;26;48;07 - 00;27;13;18
Gary Johnston
Durban poison is one of the more common high THC strains, but other options can be found. Ask about parent genetics. Have trouble finding an African sativa? Well, plenty of strains have hybridized African genetics that predispose to a higher THC potential. Cherry pie, for example, may express a high THC content by way of its Durban poison parent and request test results.
00;27;13;20 - 00;27;40;02
Gary Johnston
Genetics alone can't promise a high THC content and cannabinoid content can vary from harvest to harvest. If possible, ask your bud tender for lab tested strains to ensure that you're indeed getting a THC rich product, THC V tetrahydrocannabinol. Therein. Some people have found that it helps as an appetite suppressant. Interesting. Another cannabinoid in our toolbox.
00;27;40;04 - 00;27;44;22
Ian
From a cannabis infused studio in the clouds. This is the Cannabis Potcast.
00;27;44;24 - 00;28;04;02
Gary Johnston
And for the next story, we are going to marijuana. Mummy.com. This was a link sent to me by listener Ken from the South Okanagan. Thanks, Ken. I appreciate you sending this long. Glad you're still here. Cannabis affects internal temperature regulation. Can cannabis make you feel cold or can cannabis make you feel hot? The answer to both questions is yes.
00;28;04;04 - 00;28;26;21
Gary Johnston
Cannabis can make you feel cold, but it can also make you feel hot. Marijuana affects thermal regulation or the body's ability to control its internal temperature. A drop in body temperature after consuming cannabis is actually common. Cannabis can even make you shiver. This phenomenon is sometimes referred to as weed chills or high chills, but technically it's called THC induced hypothermia.
00;28;26;23 - 00;28;51;12
Gary Johnston
Don't be alarmed by the word hypothermia. We're not referring to the medical emergency. THC induced hypothermia is a mild decrease in body temperature caused by THC. Sometimes the drop is just enough to cause shivering. If, after using cannabis, you feel like you're shaking. You may actually be shivering from the THC, lowering your internal body temperature. Research also suggests the THC can cause the body to stop producing heat.
00;28;51;14 - 00;29;16;23
Gary Johnston
This can contribute to cold hands or cold feet after smoking marijuana. But wait. Cannabis could also make you feel hot. It varies from person to person and appears to be dose dependent. In some situations, cannabis can cause the opposite reaction. Cannabis doesn't exactly lower body temperature. Small doses of cannabinoids CBD especially appear to increase body temperature in an effect called cannabinoid induced hyperthermia.
00;29;16;23 - 00;29;47;10
Gary Johnston
Mania. Consuming small amounts of marijuana can make you feel hot. High CBD strains are more likely to increase body temperature. Research is still limited because the federal classification of cannabis. However, studies indicate the thermoregulation effects of cannabinoids are dose dependent. The amount of cannabis consumed determines the effects of body temperature. If you consume a large dose of cannabinoids, like the amount of THC needed to feel high, then it will likely lower your body temperature, causing THC induced hypothermia.
00;29;47;13 - 00;30;07;24
Gary Johnston
If, however, you microdose using small amounts of marijuana, the cannabis can actually increase your body temperature causing cannabinoid induced hyperthermia instead. Why does marijuana make people feel cold? Here's a funny story A few years ago, a friend, our children, and I took a trip to Niagara Falls, and on the way, we stopped at Duff's Wings to try their famed buffalo wings.
00;30;07;26 - 00;30;24;18
Gary Johnston
My daughter used a toothpick to taste a drop of Duff's Death Sauce hot sauce. She cringed at the unbearable heat. My friend laughed at her cautious consumption. And then, in a show of manly strength, he plunged a French fry deep into the deep sauce and pumped it into his mouth. The kids and I stared at him, jaw dropped.
00;30;24;20 - 00;30;41;29
Gary Johnston
It's not that bad. He tried to pretend, but within seconds sweats dripped from his face and neck, and a short bit later he was bleary eyed and vomiting in the bathroom. The death sauce didn't kill him, but for the rest of the drive to Niagara Falls, he was uncomfortably warm because eating chili peppers could make you feel hot.
00;30;42;01 - 00;31;08;25
Gary Johnston
He was suffering from capsaicin induced hyperthermia. What chili peppers and THC have in common? Well, just like eating chili peppers can affect your body temp, cannabinoids can affect your body temperature, too. Chili peppers increase body temperature because they contain capsaicin, the component that gives chili peppers their heat. Capsaicin activates the trp A1. Now, inside the human body are transient receptor potential channels the TRP.
00;31;09;02 - 00;31;34;16
Gary Johnston
These are basically pathways for specific molecules. When the specified molecule enters these pathways, for example Camp as case in via hot sauce, the individual experiences physiological effects. The TRP channel plays a role in sensory perceptions like taste, temperature, and pain. Cannabis also causes a blood pressure drop. It might be more than the TRP channels. Cannabis also causes a decrease in blood pressure or hypertension.
00;31;34;16 - 00;31;57;16
Gary Johnston
One of the most common signs of hypertension, or low blood pressure is feeling cold. Remember, all of cannabis side effects are strain dependent. Different strains cultivars can make you feel differently, and the effects of a strain can also vary from person to person. Strains containing varying concentrations of cannabinoids a high CBD strain can cause extremely different physiological effects than a high THC strain.
00;31;57;19 - 00;32;22;16
Gary Johnston
All side effects of cannabis, including thermoregulation and blood pressure control, differ depending on the cultivar and dosage, and, in conclusion, which yields are likely a combination of multiple physiological effects. After consuming cannabis, the body temperature decreases and the body slows or ceases to produce heat, while the blood pressure also drops. These factors, combined with an increased awareness of sensory perception, can make someone feel cold after smoking marijuana.
00;32;22;19 - 00;32;43;22
Gary Johnston
Cannabis can and does affect your internal body temperature. Cannabis can make you feel cold, or it can make you feel hot, depending on how much you consume. Don't like feeling cold? Well, decrease your THC consumption. Maybe choose a strain higher in CBD, or try adding hemp based CBD oil. Otherwise, just grab a sweater before you light up. Or if you're in a hurry to heat up, try some hot sauce.
00;32;43;24 - 00;33;08;11
Gary Johnston
And that was an interesting story from marijuana mommy.com. I had no idea the THC was partly regulating your body temperature. Thanks for that, Ken. I appreciate that. After striking a.com we go for this story. This written by David Brown, a cannabis retailer in Ontario, will have to pay $100,000 fine for pursuing and accepting prohibited payments from licensed cannabis producers.
00;33;08;14 - 00;33;31;22
Gary Johnston
The decision, posted by the Alcohol and Gaming Commission of Ontario, the Agco, on November 19th, comes following the issuance of an administrative penalty to Cannabis Express in April of 2024 of $200,000. The cannabis retailer, which operates 14 locations in Ontario and three in New Brunswick, had appealed that decision. Cannabis express has now withdrawn its appeal, says the AGC.
00;33;31;22 - 00;34;02;02
Gary Johnston
Oh, with the retailer admitting that some of the data agreement effectively induced it to purchase the relevant products from Canadian cannabis producers. The provincial regulatory agency began investigating after receiving information about possible inducement activity. The Agco investigated Cannabis Express, including a review of over 82,000 relevant documents. The agency found that Cannabis Express Data Services program and or other agreements with licensed cannabis producers are actually an inducement program.
00;34;02;04 - 00;34;27;13
Gary Johnston
Ontario's AG inducement rules exist to protect small businesses and consumers from predatory pay to play schemes, said Doctor Karen Schnur, registrar and CEO of Agco. The Agco will continue to monitor business arrangements between licensed retailers and producers, and will take strong action against any licensee found to be engaging in illegal behavior. A representative from Cannabis Express was not immediately available for comment.
00;34;27;16 - 00;34;51;12
Gary Johnston
The CEO says between January 21st and July 23rd, Cannabis Express entered into agreements or arrangements with at least 61 LPs, the majority of which were referred to as data sharing agreements or data agreements. Data on cannabis sales, especially from larger change with numerous locations, can be valuable for two producers, allowing them to better understand what products are selling well and where.
00;34;51;14 - 00;35;23;13
Gary Johnston
So-called data deals have been controversial in the industry for some time. With some Ontario retailers calling out the practice last year, provincial rules do allow retailers to sell data to producers. The OCS began sharing similar information earlier this year in a move that some hope would address these market demands. Although Cannabis Express agreements appeared on the surface to be related to the sale of such sales data, the Agco says that the fees to be paid under some of the agreements were based on the number of stock keeping units, or SKUs to be carried at Cannabis Express stores.
00;35;23;15 - 00;35;45;19
Gary Johnston
Cannabis express communications with cannabis producers continues. The Agco implied that these companies could expect to enhance sales volumes in their stores by entering into these data deals. According to the Agco, the company represented to the cannabis producers that our goal is to have long term relationships with a limited number of suppliers and pump as much volume as we can out of the stores.
00;35;45;22 - 00;36;09;02
Gary Johnston
An email shared with Strack and from Cannabis Express by a cannabis producer confirms the same language, which also stated that the fee for the data depends on a few factors, such as the product category and total number of SKUs. The ag CEO also alleges that some Canadian cannabis companies, or LPs, were told that the retailer was not willing to purchase the cannabis products without entering into data agreement.
00;36;09;04 - 00;36;35;11
Gary Johnston
Other cannabis companies that tried renegotiate Terminator altered the terms of their data. Agreements with Cannabis Express say they saw the purchase of their cannabis products decline in volume and frequency. Cannabis express retail staff were also allegedly informed that before they stocked new products, they were to confirm whether the LP had a data agreement in place. Cannabis express retail staff were also said to have been told not to mention deals of any sort, to customers or brand reps.
00;36;35;17 - 00;36;56;28
Gary Johnston
We don't have a deal with or if someone asks why we don't have stock a certain brand, just politely say we have the maximum amount of SKUs we're able to get at the moment, or something along those lines. Some publicly traded cannabis companies report sales of their own data programs, and Ontario's rules allow retailers to sell data to producers, allowing them to better understand product sales trends.
00;36;57;01 - 00;37;01;01
Gary Johnston
So a $100,000 fine for their data deals?
00;37;01;28 - 00;37;08;05
Gary Johnston
I wonder if they're rethinking that going forward.
00;37;08;07 - 00;37;30;07
Gary Johnston
As we find ourselves coming to the conclusion of another episode, again, thank you so much for being here. I appreciate it, and I think it's time to make you think a little bit. Before we finish off this episode, some more quotes about marijuana. Marijuana is like a deck of cards. Every time you indulge, you're dealt a new hand and it's up to you to play it well.
00;37;30;09 - 00;37;55;21
Gary Johnston
Smoking marijuana is like sitting down with an old sage. It's a chance to learn from the wisdom of the ages. Smoking weed is like a Pandora's box. You never know what's inside, but once you open it, you're in for an adventure. Getting high on marijuana is like taking a trip to the Oracle. It can reveal hidden truths and help you see the world in a new light.
00;37;55;23 - 00;38;08;24
Gary Johnston
And I hope you now see the world in a new light. One talk at a time. From the guy in the clouds. That's it for episode 183 of the Cannabis Potcast.
00;38;08;26 - 00;38;17;05
Ian
From the cannabis infused studio high above the Okanagan Valley. This was the Cannabis Potcast.